View Important Safety Information

Prescribing Information

Navigation

Match the dose to the individual
patient’s needs

Use sliding scale below to select patient's weight

Patient Weight (kg)
Patient Weight (lbs)
Recommended dosing and titration schedule
(each dose to be given 3 times daily)
Dose Level Approx. Dose, by Weight mg mL
1 (~0.02 mg/kg) mg mL
2 (~0.04 mg/kg) mg mL
3 (~0.06 mg/kg) mg mL
4 (~0.08 mg/kg) mg mL
5 (~0.10 mg/kg) mg mL

Dosing Instructions for CUVPOSA

  • CUVPOSA must be administered by caregivers or clinicians with an accurate measuring device
  • CUVPOSA should be dosed at least 1 hour before or 2 hours after meals
    – The presence of high-fat food reduces the oral bioavailability of CUVPOSA if taken shortly after a meal
  • Initiate dosing of CUVPOSA at 0.02 mg/kg orally 3 times daily

Titration Instructions for CUVPOSA

  • CUVPOSA should be titrated over a 4-week period based on therapeutic response and adverse reactions in increments of 0.02 mg/kg every 5 to 7 days according to the recommended dose titration schedule
  • The maximum recommended dosage is 0.1 mg/kg 3 times daily (not to exceed 1.5 to 3.0 mg per dose based upon weight)
    – For greater details, please see the full Prescribing Information
  • Prescribers should review the tolerability of the current dose level with the patient's caregiver prior to any dose increase